Nature's Nurse, Inc.

Research Articles in Support of Skingard™ Efficacy
(Active Ingredient:  Rhizophora mangle L.  v.  r samoensis, r. selala, r.stylosa)
Supplement Structure/Function Statement: Supports Skin’s Natural Repair Functions

Efficacy of Rhizophora mangle aqueous bark extract in the healing of open surgical wounds, O Fernandez, J.Z Capdevila, G Dalla, G Melchor, Fitoterapia, Volume 73, Issues 7–8, December 2002, Pages 564-568

Chandrasekaran, M., Kannathasan, K., Venkatesalu, V., Prabhakar, K., Published Online: 19, October, 2008,  Antibacterial activity of some salt marsh halpophytes and mangrove plants against methicillin resistant Stapholococcus aureus, Springer-Science + Business Media B.V.

de Armas, E., Sarracent, Y., Marrero, E., Fernandez, O., Branford-White, C., 2006, Efficacy of Rhizophora mangle aqueous bark extract (RMABE) in the treatment of apthous ulcers:  a pilot study, Current Medical Research and Opinion, 21(11), pp. 1711-1715.

Sanchez Perera, M.L., Varcalcel, L., Escobar, A., Noa, M., Polyphenol and Phytosterol Composition in an Antibacterial Extract from Rhizophora mangle, L. Bark, Journal of Herbal Pharmacotherapy, Vol. 7 (3-4), 2007

Hicks, M., Bailey, M.A., Thiagarajan, T.R., Troyer, T. L., Huggins, L.G., 2011, Antibacterial and Cytotoxic Effects of Red Mangrove (Rhizophora Mangle L. Rhizophoraceae) Fruit Extract, European Journal of Scientific Research, 63(3): pp 439-446.

Berenguer, B., Sanchez, L.M., Quilez, A., Lopez-Barreiro, M., de Haro, O., Galvez, J., and Martin, M. J., Protective and Antioxidant effects of Rhizophora mangle, L. against NSAID-induced gastric ulcers, 2005, Journal of Ethno-Pharmacology, 103 (2006), 194-200.

Lyu,S., Rhim, J., Park, W., 2005, Antiherpetic activities of flavonoids against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) in vitro, Archives of Pharmacology Research, 28, 11, 1293-1301.

Antioxidant activity of Rhizophora mangle bark
Fitoterapia, Volume 77, Issue 2, February 2006, Pages 141-143
Janet Sánchez, Gleiby Melchor, Gregorio Martínez, Arturo Escobar, Roberto Faure

Mechanisms of action underlying the gastric antiulcer activity of the Rhizophora mangle L. Journal of Ethnopharmacology, Volume 139, Issue 1, 6 January 2012, Pages 234-243Felipe Meira de-Faria, Ana Cristina Alves Almeida, Anderson Luiz-Ferreira, Ricardo José Dunder, Christiane Takayama, Maria Silene da Silva, Marcelo Aparecido da Silva, Wagner Vilegas, Ariane Leite Rozza, Cláudia Helena Pellizzon, Walber Toma, Alba Regina Monteiro Souza-Brito

Kelly, G. S.  Quercetin Monograph.   2011.  Alternative Medicine Review.  16(2):172-194.

Cho, S., Park, S., Kwon,M., Jeong,T., Bok, S., Choi, W., Jeong, W., Ryu, S., Do, S., Lee, C., Song, J., Jeong, K.  2003.  Quercetin suppresses proinflammatory cytokine production through MAP kinases and NF-κBpathway in lipopolysaccharide-stimulated macrophage.   Molecular and Cellular Biochemistry 243: 153–160.

Antibacterial activity of Rhizophora mangle bark
Fitoterapia, Volume 72, Issue 6, August 2001, Pages 689-691
Gleiby Melchor, Mabelin Armenteros, Octavio Fernández, Eliana Linares, Ivis Fragas

COX-2 and sPLA2 inhibitory activity of aqueous extract and polyphenols of Rhizophora mangle (red mangrove)
Fitoterapia, Volume 77, Issue 4, June 2006, Pages 313-315
Evangelina Marrero, Janet Sánchez, Elizabeth de Armas, Arturo Escobar, Gleiby Melchor, M.J. Abad, Paulina Bermejo, Angel M. Villar, J. Megías, Maria J. Alcaraz

Odio, A. D., Gonzalez, J. E. , Sanchez, M. L., Delgado, N. G. , Genotoxic assessment of aqueous extract of Rhizophora mangle L. (mangle rojo) by spermatozoa head assay

List, R., Patent Application Document, Application Number: EP2010/053096….An adhesive patch according to any one of claims 2 and 4, wherein said at least one therapeutic agent comprises red mangrove.  (Herpes treatment)